Thalassemia carrier status and groundwater iron: Implication for iron supplementation program for children in Bangladesh

Background: Thalassemia, a congenital disorder of hemoglobin synthesis is characterized by low and high iron status, prevalent in Bangladesh. Iron, consumed through drinking groundwater also increases the population status The study examined effect containing micronutrient powder (MNP) on ferritin Bangladeshi children with thalassemia their non-thalassemia peers exposed to concentration from groundwater. Design methods: Three hundred twenty-seven aged 2–5 years were recruited for an MNP efficacy trial. A sub sample ( n = 222) screened thalassemia. Hemoglobin levels measured without Intake key sources—diet, was measured. Mann Whitney t-test employed compare groups. Results: at endpoint remained unchanged relative baseline; 11.56 ± 0.59 g/dL (Endpoint) versus 11.6 0.54 (Baseline), p 0.83. In tended increase; 12.54 0.72 12.41 (baseline), 0.06. Baseline reserve body significantly 0.03) higher carriers (594 gm) compared non-carrier (558 gm). increase infection-adjusted baseline 7.37% 0.7) 10.17% 0.009) carrier groups respectively. Conclusions: Bangladesh, coexistence exposure renders anemia prevention program potentially lesser hazardous carriers.